My PreSonus Firewire hardware is not working on my PC.
Check you chipsets. According to PreSonus, laptops with the ATI Mobility Radeon 9000/9100 IGP chipset have shown consistent problems with pops/clicks on playback. You can check for this chipset in the Device Manager/Display Adapters. We strongly recommend that you do not get a system with this chipset, as there is not currently a workaround for this incompatibility.
(from: http://www.presonus.com/compatibility.html )
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