Q: “I’m using Reason on my PowerBook and some of the keyboard shortcuts don’t seem to work. Is there a preference or something I need to change?”
A: If You use a PowerBook (or any notebook that doesn’t have a “proper” numerical keypad) you will be unable to use some of the Keyboard Shortcuts for the sequencer that uses these numerical keys, such as:  Go to Loopstart,  Go to loop end etc. The embedded numerical keypad, using e.g. the [fn] key and the J, K, or L keys on an Apple Powerbook will not work. If you connect a USB computer keyboard that has a separate numerical keypad, you will be back in action.