“After installing an Mbox system on my Mac I can no longer put it to sleep. What gives?”
Under OSX, there is no way (currently) for the Digidesign hardware to reacquire the software when coming out of a “deep sleep” (Deep sleep is when the user forces the system to sleep by selecting Sleep from the OS X Apple menu). Thus, Digidesign has disabled this feature while any of its hardware is installed or connected. Even if you could put the Mac to sleep, a reboot would still be required before the hardware could reacquire the software.