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PreSonus StudioLive 64S 64-channel Digital Mixer Certified Open Box

64-channel Digital Mixer with 32 Microphone Preamps, 33 Motorized Faders, 64-in/64-out USB Audio Interface, AVB Networking, FLEX DSP Engine, SD Card Recorder, DAW Control
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Item ID: SL64Sd16
PreSonus StudioLive 64S 64-channel Digital Mixer
PreSonus StudioLive 64S 64-channel Digital Mixer

Condition Notes:

This returned item is cosmetically in excellent condition. Some of the original accessories are missing, including the ethernet cable. The item ships in its original packaging which shows some signs of wear.

This item was thoroughly inspected by our factory-authorized service team and is backed by Sweetwater's exclusive 2-year warranty. The images shown do not necessarily represent the condition of this particular item.

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The Most Formidable StudioLive Yet

The StudioLive 64S is a powerhouse — it’s PreSonus’s most formidable offering yet. This 64-channel digital mixer boasts a quad-core FLEX DSP engine with enough muscle to drive 526 simultaneous processors, and then some. What’s more, its FLEX FX multi-effects processor vaunts eight slots of reverb emulations and delays with eight dedicated effects buses. Benefit from easy expandability thanks to built-in AVB networking. Enjoy versatile operation by virtue of the 64S’s 32 Flex Mixes. Shape and polish each channel to perfection courtesy of PreSonus’s lauded Fat Channel processing.

Related Videos: StudioLive 64S 64-channel Digital Mixer

Quad-core FLEX DSP engine boasts impressive processing muscle

The StudioLive 64S is packed with serious power. Its quad-core FLEX DSP engine possesses enough processing muscle to run 526 simultaneous processors, 43 mix buses, and 76 mixing channels. And its FLEX FX multi-effects processor includes eight slots of reverb emulations and delays with eight dedicated effects buses. At Sweetwater, we’re impressed by the sheer amount of raw power that’s lurking under the 64S’s hood.

Three options for multitrack recording

The PreSonus StudioLive 64S gives you three efficient options for multitrack recording. A built-in SD card recorder allows you to record all inputs simultaneously, and you can also play back from the SD card to do virtual soundchecks without a computer. You can also connect to a computer via USB for 64 channels of recording and playback — almost twice that of previous generations. And the StudioLive 64S supports AVB over Ethernet too, enabling you to interface directly with PreSonus NSB stage boxes, EarMix 16M personal monitor mixers, and SW5E AVB switches.

Pristine XMAX preamps for sound reinforcement and recording

Simply put, the 32 Class A XMAX preamps onboard the StudioLive 64S sound like they belong in the studio. Their high headroom and low noise floor deliver extremely clean and clear sound you simply wouldn’t expect from a live console. And mic preamp settings are fully recallable, which is a huge time saver when you mix or record the same band or show on a regular basis.

Flex Mixes offer a ton of freedom for any mixing application

It can be frustrating trying to use the same mixer for many different tasks. Thanks to Flex Mixes, that’s not the case with the PreSonus StudioLive 64S. Flex Mixes can be set up as aux mixes, subgroups, or matrix mixes, depending on what your show demands. Need a ton of different monitor mixes for a large group of musicians? No problem, you can create up to 32 aux sends if you need to. Same with subgroups and matrix mixes — perfect for theater productions and multi-zone venues, respectively. Basically, the 64S’s Flex Mixes allow you to adapt your mixer to the mixing task at hand, instead of adapting your workflow to the limitations of your mixer.

Advanced processing for EQ, compression, and effects

The StudioLive series of consoles has always been known for outstanding effects and processing capabilities, and the StudioLive 64S takes it even further. Its FLEX FX multi-effects processor supplies you with eight internal effects buses that are loaded with a combination of reverbs, delays, and other effects that you can route any channel through. On top of that, Fat Channel processing offers vintage EQ and compressor models on every channel. And if you crave even more plug-in processing power, you can bolster your 64S with PreSonus’s Fat Channel Collection (sold separately).

PreSonus StudioLive 64S Features:

  • 64-channel digital mixing console with built-in SD card recorder
  • Quad-core FLEX DSP engine possesses enough processing muscle to run 526 simultaneous processors, 43 mix buses, and 76 mixing channels
  • Record and play back up to 64 channels via USB — almost twice that of previous generations
  • Supports AVB over Ethernet for use with PreSonus NSB stage boxes, EarMix 16M personal monitor mixers, and SW5E AVB switches
  • Built-in SD card support for multitrack recording and virtual soundchecks
  • Main Left, Right, and Mono/Center buses with per-channel mono send level and center divergence control
  • Fully recallable XMAX preamps with ultra-low noise floor
  • 33 touch-sensitive motorized faders allow you to mix with precision
  • 24 DCA groups help you manage complex productions with high channel counts
  • FLEX FX multi-effects processor vaunts 8 slots of reverb emulations and delays with 8 dedicated effects buses
  • Fat Channel processing provides vintage EQ and compression options for each channel
  • Better visual feedback than ever, with full-color touchscreen and channel scribble strips
  • Advanced scene management helps you manage complex mixing tasks more efficiently
  • 32 Flex Mixes can be used as aux mixes, subgroups, or matrix mixes
  • Bundled software includes a Fender Studio Pro perpetual license
What is Certified Open Box Gear?

At Sweetwater, we're so picky that what we call "Certified Open Box" is actually better than what most music retailers sell as "new" gear! Our gear hasn't endured hundreds of people a week plunking away at all the keyboards, fumbling through Stairway to Heaven on every guitar or playing with every fader and knob on a mixer or control surface.

Certified Open Box (also known as a demo) means we’ve had it out of the box for our YouTube channel, displayed at events, tested in our studio, or maybe it was in a customer’s hands for a few days and isn’t ‘factory fresh’ as a result. Every Certified Open Box item we sell has Sweetwater’s 2-year Total Confidence Coverage™ warranty and has been tested and verified up to ‘new’ specs by our factory-authorized technicians to make sure it’s in perfect working order before we ship it to you.

When you buy a Certified Open Box item at Sweetwater, you get:
  • 2-year Total Confidence Coverage Warranty™!
  • Products inspected and tested by our factory-authorized techs, guaranteed to function like new (or better)!
  • FREE shipping on most items
  • Equipment that will MEET or EXCEED your expectations!

Click HERE to browse our current inventory of Certified Open Box equipment. Purchasing Certified Open Box gear from Sweetwater is a smart and safe way to save!

Resources

6 Best Digital Mixing Consoles Under $5,000
Mar 12, 2026
PreSonus StudioLive 64S Digital Mixer Overview
Mar 26, 2019

Warranty Info

Sweetwater's FREE 2-Year Total Confidence Coverage Warranty

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  • Save money with FREE parts and labor
  • Get back to making music with the industry's fastest turnaround time
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Tech Specs

  • Type: Digital Mixer
  • Channels: 64
  • Inputs - Mic Preamps: 32 x XLR-1/4" combo (mic/line)
  • Phantom Power: 32 Channels
  • Inputs - Line: 1 x Dual RCA Stereo (tape), 4 x 1/4" (2 x stereo aux in)
  • Outputs - Main: 2 x XLR (main out), 1 x XLR (mono/center), 2 x 1/4" (monitor)
  • Outputs - Other: 16 x XLR (mix out), 1 x Dual RCA Stereo (tape)
  • Outputs - Digital: 1 x XLR (AES/EBU)
  • Busses/Groups: 32 x FlexMix Buses (aux, subgroup, matrix), 43 total mix buses, 24 x DCA groups
  • Talkback: 1 x XLR (phantom power)
  • Data I/O: 1 x Locking Ethernet (AVB audio network), 1 x RJ45 (network control)
  • Headphones: 1 x 1/4"
  • USB: 1 x Type B (64 x 64)
  • Computer Connectivity: USB 2.0
  • Bluetooth: v4.1
  • Faders: 33 x Touch-sensitive motorized faders
  • A/D Resolution: 24-bit/48kHz
  • Effects: FLEX FX Multi-effects processor, 8 x effects slots, 8 x effects buses
  • Signal Processing: Fat Channel plug-ins, 10 x EQs, 10 x Compressors
  • Features: Metro remote-control (UC 4.2)
  • Transport Controls: Yes
  • DAW Control: Advanced Studio One, MCU Logic emulation, HUI Pro Tools emulation
  • Screen: 7" Touchscreen
  • Storage: SD card recorder (34 track)
  • Software: Fender Studio Pro
  • Power Source: Standard IEC AC cable
  • Height: 6.51"
  • Depth: 22.97"
  • Width: 32.37"
  • Weight: 37.2 lbs.
  • Manufacturer Part Number: 2779200404

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Reviews

4.4

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What I've been waiting on
This Mixer is great !!! I've had it now for a couple of months and couldn't be happier. This integrates with Studio One and the number of options are incredible. I still learning how work everything, went from a Tascam DM4800 / Pro Tools to this setup also using an Studiolive 32R mixer to get an full 64 Track count fully integrated using an AVB switch and so far this has worked with no issues. This has enabled me to be more efficient in my home studio …. well worth the change …. I also have to give an shout out to the Sweetwater team for helping me achieve this 'Thanks guys"
by Shawn Holyfield from Charlotte on
Music background: Working musician / producer / writter .... been working at it for 30 years & still going
Game changer
Our chur h has been using the whole Presonus ecosystem for a little over a year now. It has been a game changer for us. Easy for our volunteers to control and we have personal monitoring for everyone and our livestream audio sounds great. All from the same system. Love the 64s! Great tool for our church to achieve excellence, especially at the price point.
by Scott from O’Fallon Mo on
Music background: Worship Pastor
Even better than I expected
I thought this PreSonus StudioLive III 64S digital mixer/console would be good, maybe even great, but it has exceeded all my expectations.

I bought this console for studio use as it was my goal to simplify my setup and eliminate all of my outboard gear. In pursuits of this goal I also purchased the PreSonus NSB8.8 and NSB16.8 AVB Networked Stage Boxes and several PreSonus EarMix 16 personal monitor boxes, among other items in the PreSonus ecosystem. I love the idea of the AVB networking setup using CAT5 cabling and dumping my clunky XLR snake boxes.

In a nutshell, the StudioLive III 64S and the Presonus ecosystem of connecting products offers a complete solution that meet all of my goals: a great sounding, versatile, expandable, and simplified studio setup that I can easily tailor to my workflow.
by Bob McCarroll from Phoenix on
Music background: Musician, Audio Engineer, Producer.
workhorse that sounds great
Have had ours for 2 years now. It replaced our Yamaha M7CL and gave us a big improvement in sound quality and overall routing flexibility. I really like the fat channel sounds and the effects are ok. Our (church) online livestream is now actually sounding good!
by Eric from MD on
Music background: Worship tech, guitar
The very best in this range price
If you need to deal with lots of channels with a moderate budget, there is not best deal than 64s, I have been using it for a year, easy to set up, clean sound and a lot of aux…
by Ernesto Gallardo on
Music background: Music conductor , arranger, sound guy, producer

Sweetwater and PreSonus go way back, and that makes a lot of sense. Like Sweetwater, PreSonus is largely staffed by active musicians, songwriters, live sound techs, and engineers, and like Sweetwater, their culture shows up in everything they do. Early on, PreSonus broke ground by offering super-affordable audio interfaces that brought quality recording to home studio engineers everywhere. In the following years, we've been with them as they introduced a powerful, artist-friendly DAW, groundbreaking digital mixers, and more - all products we at Sweetwater use ourselves. One thing that's never changed, even as PreSonus has branched out into new territory, is that they've always done everything possible to provide you with the best value, and we're proud to stand by their products.

See also: Mixers Digital, PreSonus, PreSonus Digital Mixers