After doing quite a bit of research, I determined that the US-144 has the exact same features as the Mbox 2 minus Pro Tools LE support. This didn't bother me much, let the "Pros" pay "Pro" prices for Pro Tools LE/HD. I purchased this unit to record my 3 piece rock group and I haven't been let down yet! Of course I have to lay drums down seperately but im still reveling over the price tag. The ASIO drivers work incredibly well with the DAW programs I have used (Ableton Live! 7, Cubase, Nuendo, even various others). Latency is extremely low which surprised me as this is a USB interface. I have reccomended this to a few friends. One went out and purchased it within a week and is as impressed as I am! Overall, great product, I can't reccomend this enough!