Best in this range
For audio comparison and "A-B-ing" tests, I own a ATH-M50x, AKG K240, Sennheiser hd650, and Beyerdynamic DT 770 Studio. The K240 and hd650 are open back so not apples to apples. But the 770 and m50X are similar closed back like the HD 280 Pros.
For my ears the hd650 are amazing, VERY flat, smooth accurate, super detailed, the best for truly accurate listening and mixing. I use them to compare sound of other cans.
The only closed back sets I have found that are even close in sound to the hd650's are the HD280's. No, they do not sound the same but they have the most natural mid range and hi end of the other two closed back I own. To me the M50x phones are very hyped in the high end and low end, mids seem scooped. The 770's have better mid range and hi end but a tad less low end than the 280's.
I like the larger ear cups of the HD280's and 770's. The smaller ear cushions on the M50x's are not as comfortable. The M50x's may be better for tracking due the the more pronounced hi end, but for general listing they are to hyped for me...almost harsh.
As far as tracking with drums, non of these closed back are great at blocking out loud drumming but I find the HD280's a tad better than the 770's and M50x's.
Between the 3 closed back can's I own the HD280 are the most comfortable. All around if I'm traveling, mixing live etc and can only take one set of can's with me, I always go for the HD280's.