I've tried this pedal with an American Deluxe Strat, a Music Man Albert Lee (w/ 2 dimarzio hb), an American special tele and a Gibson SG. I've gotta say that it sounded really good with all of them. The presence control makes it very easy find the best tone. There's a lot of drive in there but you don't have to use it all the way down if you don't want to. My preferred settings is with the drive at 2 o'clock (60%). The tone control is very responsive. I liked it a lot with the tone at 3 and the presence at 9.