In some instances, we have found that when using Vienna Instruments' monumental Symphonic Cube with an M-Audio USB controller, the two won't always communicate. There are two simple fixes you can try: First, unplug the USB cable from the controller for a few seconds, then reconnect. You can also try moving the mod wheel up and back, which can also solve this little glitch. Try these before you resort to asking for help from Vienna Instruments' Tech Support.