This could be any number of things. This board has a lot of features and it could be any one of them not set correctly that would cause problems. Any way you can take a decent picture of the board as it is setup and then explain what specifically you have running on each channel? Otherwise, you'll probably need someone with some expertise to physically look at it.
I'm also going to ask a mod to move this into the live sound forum, where you might get more attention from people who do this professionally.
What is hip?
Gear: Digidesign 003R / Telos Zephyr XStream ISDN codec / JK Audio Broadcast Host digital phone hybrid
PC: HP 6005 Pro MT PC running Windows 7 Pro 64-bit w 3 GHz AMD Phenom II x3 B7, 4GB RAM
DAWs: Sound Forge 10 Pro, Vegas Pro 9, Adobe Audition 3.0, Pro Tools LE 8.04, Reaper x64.